Research 2019 Ver.

Research 2016 Ver.

Research 2013 Ver.

Research 2010 Ver.

Goal:

Bioresource-related technologies are important for the efficient and stable preservation and transportation of resources and for the development of new resources in response to new research trends. We develop the genetic and reproductive engineering technologies necessary for the maintenance and supply of RIKEN BRC resources, especially experimental animals and stem cells, at a high quality, and to develop new research resources. These technologies include. In addition, we offer training programs so that these technologies can be widely used by the research community.

Activities:

  1. Nuclear transfer
  2. Microinsemination
  3. Cryopreservation and related technology
  4. Stem cell technologies
  5. Animal model development

Press Release(2020-2024)

Specific Aims

Press Release(2020-2024)

2024

August 13, 2024
“Disruption of insulin receptor substrate 2 (Irs2) causes non-obese type 2 diabetes with β-cell dysfunction in the golden (Syrian) hamster”
arrowBRC Site

May 10, 2024
“Reduction of H3K9 methylation by G9a inhibitors improves the development of mouse SCNT embryos”
arrowBRC Site

April 26, 2024
“Superovulation with an anti-inhibin monoclonal antibody improves the reproductive performance of rat strains by increasing the pregnancy rate and the litter size”
arrowBRC Site

2023

October 30, 2023
“Effect of microgravity on mammalian embryo development evaluated at the International Space Station.”
BRC Site

2022

May 19, 2022
“Birth of mice from meiotically arrested spermatocytes following biparental meiosis in halved oocytes”
arrowRIKEN Site (Research Highlight) arrowBRC Site

April 28, 2022
“An epigenetic cause of miscarriages is identified and cured in mice”
arrowRIKEN Site (Press Release) arrowBRC Site

January 18, 2022
“Highly rigid H3.1/H3.2-H3K9me3 domains set a barrier for cell fate reprogramming in trophoblast stem cells”
arrowRIKEN Site (Research Highlight) arrowBRC Site

2021

September 7, 2021
“Formation of spermatogonia and fertile oocytes in golden hamsters requires piRNAs”
arrowBRC Site  arrowIMG of the Czech Academy of Sciences Site

2020

May 1, 2020
“Loss of H3K27me3 imprinting in the Sfmbt2 miRNA cluster causes enlargement of cloned mouse placentas”
arrowRIKEN Site (Research Highlight)