Goal:
Bioresource-related technologies are important for the efficient and stable preservation and transportation of resources and for the development of new resources in response to new research trends. We develop the genetic and reproductive engineering technologies necessary for the maintenance and supply of RIKEN BRC resources, especially experimental animals and stem cells, at a high quality, and to develop new research resources. These technologies include. In addition, we offer training programs so that these technologies can be widely used by the research community.
Activities:
- Nuclear transfer
- Microinsemination
- Cryopreservation and related technology
- Stem cell technologies
- Animal model development
Press Release(2020-2024)
Specific Aims
Press Release(2020-2024)
2024
August 13, 2024
“Disruption of insulin receptor substrate 2 (Irs2) causes non-obese type 2 diabetes with β-cell dysfunction in the golden (Syrian) hamster”
BRC Site
May 10, 2024
“Reduction of H3K9 methylation by G9a inhibitors improves the development of mouse SCNT embryos”
BRC Site
April 26, 2024
“Superovulation with an anti-inhibin monoclonal antibody improves the reproductive performance of rat strains by increasing the pregnancy rate and the litter size”
BRC Site
2023
October 30, 2023
“Effect of microgravity on mammalian embryo development evaluated at the International Space Station.”
BRC Site
2022
May 19, 2022
“Birth of mice from meiotically arrested spermatocytes following biparental meiosis in halved oocytes”
RIKEN Site (Research Highlight) BRC Site
April 28, 2022
“An epigenetic cause of miscarriages is identified and cured in mice”
RIKEN Site (Press Release) BRC Site
January 18, 2022
“Highly rigid H3.1/H3.2-H3K9me3 domains set a barrier for cell fate reprogramming in trophoblast stem cells”
RIKEN Site (Research Highlight) BRC Site
2021
September 7, 2021
“Formation of spermatogonia and fertile oocytes in golden hamsters requires piRNAs”
BRC Site IMG of the Czech Academy of Sciences Site
2020
May 1, 2020
“Loss of H3K27me3 imprinting in the Sfmbt2 miRNA cluster causes enlargement of cloned mouse placentas”
RIKEN Site (Research Highlight)