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  1. Hirose M, Inoue K, Matoba S, Tatebe T, Tokita S, Dodo Y, Tomishima T, Hasegawa A, Honda A, Ozaki M, Shinogi A, Yanagisawa R, Fauzi M, Murakami T, Inagaki N, Tamura M, Ogura A. Disruption of insulin receptor substrate 2 (IRS2) causes non-obese type 2 diabetes with β-cell dysfunction in the golden (Syrian) hamster. Sci Rep, 10.1038/s41598-024-67513-9, 2024. arrowRIKEN Site (Press Release, Japanese) arrowBRC Site (Japanese) arrowBRC Site (English) arrowScientific Reports Site
  2. Guo Y, Kitano T, Inoue K, Murano K, Hirose M, Li TD, Sakashita A, Ishizu H, Ogonuki N, Matoba S, Sato M, Ogura A, Siomi H. Obox4 promotes zygotic genome activation upon loss of Dux. eLife, 13:e95856, 2024
  3. Mochida K, Morita K, Sasaoka Y, Morita K, Endo H, Hasegawa A, Asano M, Ogura A. Superovulation with an anti-inhibin monoclonal antibody improves the reproductive performance of rat strains by increasing the pregnancy rate and the litter size. Sci Rep, 14: 8294, 2024 RIKEN SIte (Press Release, Japanese) BRC Site (Japanese) BRC Site (English)
  4. Matoba S, Shikata D, Shirai F, Tatebe T, Hirose M, Watanabe N, Hasegawa A, Ito A, Shinkai Y, Yoshida M, Ogura A. Reduction of H3K9 methylation by G9a inhibitor improves development of mouse SCNT embryos. Stem Cell Rep, 19: 906-921, 2024 RIKEN SIte (Press Release, Japanese) BRC Site (Japanese) BRC Site (English)
  5. Morimoto H, Ogonuki N, Matoba S, Kanatsu-Shinohara M, Ogura A, Shinohara T. Restoration of fertility in nonablated recipient mice after spermatogonial stem cell transplantation. Stem Cell Reports, 19: 443-455, 2024
  6. Saito A, Tahara R, Hirose M, Kadota M, Hasegawa A, Kondo S, Kato H, Amano T, Yoshiki A, Ogura A, Kiyosawa H. Inter-subspecies mouse F1 hybrid embryonic stem cell lines newly established for studies of allelic imbalance in gene expression. Exp Anim , 73: 310-318, 2024
  7. Yamatoya K, Kurosawa M, Hirose M, Miura Y, Taka H, Nakano T, Hasegawa A, Kagami K, Yoshitake H, Goto K, Ueno T, Fujiwara H, Shinkai Y, Kan FWK, Ogura A, Araki Y. The fluid factor OVGP1 provides a significant oviductal microenvironment for the reproductive process in the golden hamster. Biol Reprod 110: 465-475, 2024
  8. Kanatsu-Shinohara M, Shiromoto Y, Ogonuki N, Inoue K, Hattori S, Miura K, Watanabe N, Hasegawa A, Mochida K, Yamamoto T, Miyakawa T, Ogura A, Shinohara T. Intracytoplasmic sperm injection induces transgenerational abnormalities in mice. J Clin Invest 133:e170140, 2023
  9. Wakayama S, Kikuchi Y, Soejima M, Hayashi E, Ushigome N, Yamazaki C, Suzuki T, Shimazu T, Yamamori T, Osada I, Sano H, Umehara M, Hasegawa A, Mochida K, Yang L, Emura R, Kazama K, Imase K, Kurokawa Y, Sato Y, Higashibata A, Matsunari H, Nagashima H, Ogura A, Kohda T, Wakayama T. Effect of microgravity on mammalian embryo development evaluated at the International Space Station. iScience 26, 108177, 2023　RIKEN Site (Japanesee) BRC Site (English)BRC Site (Japanese) 
    Univ. of Yamanashi  (Press Release, Japanese)

  10. Ihashi S, Hamanaka M, Kaji M, Mori R, Nishizaki S, Mori M, Imasato Y, Inoue K, Matoba S, Ogonuki N, Takasu A, Nakamura M, Matsumoto K, Anzai M, Ogura A, Ikawa M, Miyamoto K. Incomplete activation of Alyref and Gabpb1 leads to preimplantation arrest in cloned mouse embryos. Life Sci Alliance 6: e202302296, 2023 KINDAI Univ. (Press Release, Japanese)
  11. Shimazu T, Yoshimoto R, Kotoshiba K, Suzuki T, Matoba S, Hirose M, Akakabe M, Sohtome Y, Sodeoka M, Ogura A, Dohmae N, Shinkai Y. Histidine N1-position-specific methyltransferase CARNMT1 targets C3H zinc finger proteins and modulates RNA metabolism. Genes Dev 37: 724-742, 2023
  12. Watanabe N, Hirose M, Hasegawa A, Mochida K, Ogura A, Inoue K. Derivation of embryonic stem cells from wild-derived mouse strains by nuclear transfer using peripheral blood cells. Sci Rep, 13: 11175, 2023
  13. Wickramage I, VanWye J, Max K, Lockhart JH, Hortu I, Mong EF, Canfield J, Lamabadu Warnakulasuriya Patabendige HM, Guzeloglu-Kayisli O, Inoue K, Ogura A, Lockwood CJ, Akat KM, Tuschl T, Kayisli UA, Totary-Jain H. SINE RNA of the imprinted miRNA clusters mediates constitutive type III interferon expression and antiviral protection in hemochorial placentas. Cell Host Microbe, 31: 1185-1199.e10, 2023
  14. Uemura S, Maenohara S, Inoue K, Ogonuki N, Matoba S, Ogura A, Kurumizaka M, Yamagata K, Sharif J, Koseki H, Ueda K, Unoki M, Sasaki H. UHRF1 is essential for proper cytoplasm architecture and function of mouse oocyte and derived embryo. Life Sci Alliance 6: e202301904, 2023.
  15. Miyazaki T, Kanatsu-Shinohara M, Ogonuki N, Matoba S, Ogura A, Yabe-Nishimura C, Zhang H, Pommier Y, Trumpp A, Shinohara T. Glutamine protects mouse spermatogonial stem cells against NOX1-dereived ROS for sustaining self-renewal division in vitro. Development 150: dev201157, 2023.
  16. Hirose M, Tomishima T, Ogura A. Editing the genome of the golden hamster (Mesocricetus auratus). Methods Mol Biol, 2637:247-254, 2023. doi: 10.1007/978-1-0716-3016-7_19.
  17. Uchida A, Imaimatsu K, Suzuki H, Han X, Ushioda H, Uemura M, Imura-Kishi K, Hiramatsu R, Takase H, Hirate Y, Ogura A, Azuma M, Kudo A, Kanai Y. SOX17-positive rete testis epithelium is required for Sertoli valve formation and normal spermiogenesis in the male mouse. Nat Commun 13: 7860, 2022.
  18. Shikata D, Matoba S, Hada M, Sakashita A, Inoue K, Ogura A. Suppression of endogenous retroviral enhancers in mouse embryos derived from somatic cell nuclear transfer. Front Genet, 13:1032760, 2022.
  19. Wakayama S, Soejima M, Kikuchi Y, Hayashi E, Ushigome N, Hasegawa A, Mochida K, Suzuki T, Yamazaki C, Shimazu T, Sano H, Umehara M, Matsunari H, Ogura A, Nagashima H, Wakayama T. Development of a new device for manipulating frozen mouse 2-cell embryos on the International Space Station. PLoS One 17: e0270781, 2022.
  20. Ogonuki N, Kyogoku H, Hino T, Osawa Y, Fujiwara Y, Inoue K, Kunieda T, Mizuno S, Tateno H, Sugiyama F, Kitajima T, Ogura A. Birth of mice from meiotically arrested spermatocytes following biparental meiosis in halved oocytes. EMBO Rep, 23: e54992, 2022.RIKEN Site(Japanese) BRC Site(Japanese) RIKEN Site (Research Highlight, English)
  21. Shogo Matoba, Kozuka C. Miura K. Inoue K. Kumon M. Hayashi R. Ohhata T. Ogura A. and Inoue A. Noncanonical imprinting sustains embryonic development and restrains placental overgrowth. Genes Dev, 36: 483-494, 2022. Genes Dev Site RIKEN Site(English) RIKEN Site(Japanese) BRC Site(English) BRC Site(Japanese)
  22. Hasegawa A, Mochida K, Nakamura A, Miyagasako R, Ohtsuka M, Hatakeyama M, Ogura A. Use of anti-inhibin monoclonal antibody for increasing the litter size of mouse strains and its application to i-GONAD. Biol Reprod 107: 605-618, 2022.
  23. Kanatsu-Shinohara M, Ogonuki N, Matoba S, Morimoto H, Shiromoto Y, Ogura A, Shinohara, T. Regeneration of spermatogenesis by mouse germ cell transplantation into allogeneic and xenogeneic testis primordia or organoids. Stem Cell Reports 17: 924-935, 2022.
  24. Hada M, Miura H, Tanigawa A, Matoba S, Inoue K, Ogonuki N, Hirose M, Watanabe N, Nakato R, Fujiki K, Hasegawa A, Sakashita A, Okae H, Miura K, Shikata D, Arima T, Shirahige K, Hiratani I, Ogura A. Highly rigid H3.1/H3.2–H3K9me3 domains set a barrier for cell fate reprogramming in trophoblast stem cells. Genes Dev 36: 84-102, 2022.　RIKEN Site(Japanese) Genes Dev Site RIKEN Site (Research Highlight, English)
  25. Hayashi E, Wakayama S, Ito D, Hasegawa A, Mochida K, Ooga M, Ogura A, Wakayama T. Mouse in vivo-derived late 2-cell embryos have the higher developmental competence after high osmolality vitrification and −80°C preservation compared with IVF or ICSI embryos. J Reprod Dev 67: 197-205, 2021.
  26. Loubalova Z, Fulka H, Horvat F, Pasulka J, Malik R, Hirose M, *Ogura A, *Svoboda P. Formation of spermatogonia and fertile oocytes in hamsters requires piRNAs. Nat Cell Biol (in press) IMG Site (English) RIKEN Site(Japanese)
  27. Mizuno-Iijima S, Nakashiba T, Ayabe S, Nakata H, Ike F, Hiraiwa N, Mochida K, Ogura A, Masuya H, Kawamoto S, Tamura M, Obata Y, Shiroishi T, Yoshiki A. Mouse resources at the RIKEN BioResource Research Center and the National BioResource Project Core Facility in Japan. Mam Genome (in press)
  28. Akter MS, Hada M, Shikata D, Watanabe G, Ogura A, Matoba S. CRISPR/Cas9-based genetic screen of SCNT-reprogramming resistant genes identifies critical genes for male germ cell development in mice. Sci Rep 11: 15438, 2021.
  29. Mochida K, Hasegawa A, Shikata D, Itami N, Hada M, Watanabe N, Tomishima T, Ogura A. Easy and quick (EQ) sperm freezing method for urgent preservation of mouse strains. Sci Rep 11:14149, 2021.
  30. Morimoto H, Ogonuki N, Kanatsu-Shinohara M, Matoba S, Ogura A, Shinohara T. Spermatogonial stem cell transplantation into nonablated mouse recipient testes. Stem Cell Rep 16:1832-1844, 2021.
  31. Kamimura S, Inoue K, Mizutani E, Kim J-M, Inoue H, Ogonuki N, Miyamoto K, Ihashi S, Itami N, Wakayama T, Ito A, Nishino N, Yoshida M, Ogura A. Improved development of mouse SCNT embryos by chlamydocin analogues, class I and IIa histone deacetylase inhibitors. Biol Reprod 105:543-553, 2021.
  32. Sun S, Yano S, Nakanishi MO, Hirose M, Nakabayashi K, Hata K, Ogura A, Tanaka S. Maintenance of mouse trophoblast stem cells in KSR-based medium allows conventional 3D culture. J Reprod Dev. 67:197-205, 2021.
  33. Kobayashi Y, Tomizawa SI, Ono M, Kuroha K, Minamizawa K, Natsume K, Dizdarević S, Dočkal I, Tanaka H, Kawagoe T, Seki M, Suzuki Y, Ogonuki N, Inoue K, Matoba S, Anastassiadis K, Mizuki N, Ogura A, Ohbo K. Tsga8 is required for spermatid morphogenesis and male fertility in mice. Development. 148(8): dev196212, 2021.
  34. Ogura A, Matoba S, Inoue K. Epigenetic abnormalities associated with somatic cell nuclear transfer. Reproduction 162:F45-F58, 2021
  35. Morimoto H, Yamamoto T, Miyazaki T, Ogonuki N, Ogura A, Tanaka T, Kanatsu-Shinohara M, Yabe-Nishimura C, Zhang H, Pommier Y, Trumpp A, Shinohara T. An interplay of NOX1-derived ROS and oxygen determines the spermatogonial stem cell self-renewal efficiency under hypoxia. Genes Dev 35: 250-260, 2021.
  36. Mori Y, Ogonuki N, Hasegawa A, Kanatsu-Shinohara M, Ogura A, Wang Y, McCarrey JR, Shinohara T. OGG1 protects mouse spermatogonial stem cells from reactive oxygen species in culture. Biol Reprod. 104(3):706-716, 2021. doi: 10.1093/biolre/ioaa216. Online ahead of print.Biol Reprod.site
  37. Miura K, Ogura A, Kobatake K, Honda H, Kaminuma O. Progress of genome editing technology and developmental biology useful for radiation research. J Radiation Research 62(Supplement): i53-i63.
  38. Qiu J, Hasegawa A, Mochida K, Ogura A, Koshimoto C, Matsukawa K, Edashige K. Equilibrium vitrification of mouse embryos using low concentrations of cryoprotectants. Cryobiology 98: 127-133, 2021
  39. Ishiuchi T, Abe S, Inoue K, Yeung WKA, Miki Y, Ogura A Sasaki H. Reprogramming of the histone H3.3 landscape in the early mouse embryo. Nat Struct Mol Biol 28:38-49, 2021.
    Nat Struct Mol Biol site プレス発表 (Japanese)

  40. Hasegawa A, Mochida K, Matoba S, Inoue K, Hama D, Kadota M, Hiraiwa N, Yoshiki A, Ogura A. Development of Assisted Reproductive Technologies for Mus spretus. Biol Reprod 104: 234-243, 2021.
  41. Miura K, Matoba S, Hirose M, Ogura A. Generation of chimeric mice with spermatozoa fully derived from embryonic stem cells using a triple-target CRISPR method for Nanos3. Biol Reprod 104: 223-233, 2021.
  42. Miura K, Inoue K, Ogura A, Kaminuma O. Role of CD4+ T cells in allergic airway diseases: Learning from murine models. Int J Mol Sci 21: 7480, 2020
  43. Jia R, Chen X, Zhu Z, Yu F, Huang J, Zhang L, Ogura, A, Pan J. Improving ovulation in gilts using anti-inhibin serum treatment combined with fixed-time artificial insemination. Reprod Domestic Anim 56: 112-119, 2020
  44. Tsuchimoto A, Tone M, Ogonuki N, Hada M, Ogura A, Takashima S. Germ cell depletion in recipient testis has adverse effects on spermatogenesis in orthotopically transplanted testis pieces via retinoic acid insufficiency. Sci Rep 10: 10796, 2020
  45. Kazuki Y, Gao FJ, Li Y, Moyer AJ, Devenney B, Hiramatsu K, Miyagawa-Tomita S, Abe S, Kazuki K, Kajitani N, Uno N, Takehara S, Takiguchi M, Yamakawa M, Hasegawa A, Shimizu R, Matsukura S, Noda N, Ogonuki N, Inoue K, Matoba S, Ogura A, Florea LD, Savonenko A, Xiao M, Wu D, Batista DA, Yang J, Qiu Z, Singh N, Richtsmeier JT, Takeuchi T, Oshimura M, Reeves RH. A non-mosaic transchromosomic mouse model of Down syndrome carrying the long arm of human chromosome 21. Elife 9: e56223, 2020
  46. Mizuno-Iijima S, Ayabe S, Kato K, Matoba S, Ikeda Y, Dinh TTH, Le HT, Suzuki H, Nakashima K, Hasegawa Y, Hamada Y, Tanimoto Y, Daitoku Y, Iki N, Ishida M, Ibrahim EAE, Nakashiba T, Hamada M, Murata K, Miwa Y, Okada-Iwabu M, Iwabu M, Yagami KI, Ogura A, Obata Y, Takahashi S, Mizuno S, Yoshiki A, Sugiyama F. Efficient production of large deletion and gene fragment knock-in mice mediated by genome editing with Cas9-mouse Cdt1 in mouse zygotes. Methods S1046-2023(19)30328-7, 2020
  47. Inoue K, Ogonuki N, Kamimura S, Inoue H, Matoba S, Hirose M, Honda A, Miura K, Hada M, Hasegawa A, Watanabe N, Dodo Y, Mochida K, Ogura A. Loss of H3K27me3 imprinting in the Sfmbt2 miRNA cluster causes enlargement of cloned mouse placentas. Nat Commun 11: 2150, 2020
    Nat Commun site   https://doi.org/10.1038/s41467-020-16044-8 Acrosin is essential for sperm penetration through the zona pellucida in hamsters.プレス発表 (Japanese) RIKEN Site (Research Highlight, English)

  48. Mochida K.  Development of assisted reproductive technologies in small animal species for their efficient preservation and production. (SRD Innovative Technology Award 2019) J Reprod Dev 66: 299-306, 2020
  49. Kanatsu-Shinohara M, Ogonuki M, Matoba S, Ogura A, Shinohara T. Autologous transplantation of spermatogonial stem cells restores fertility in congenitally infertile mice. Proc Natl Acad Sci USA 117: 7837-7844, 2020
    Autologous transplantation of spermatogonial stem cells restores fertility in congenitally infertile mice.PNAS Site    https://doi.org/10.1073/pnas.1914963117

  50. Hirose M,Honda A, Fulka H, Tamura-Nakano M, Matoba S, Tomishima T, Mochida K, Hasegawa A, Nagashima K, Inoue K, Ohtsuka M, Baba T, Yanagimachi R, Ogura A. Acrosin is essential for sperm penetration through the zona pellucida in hamsters. Proc Natl Acad Sci U S A
    PNAS Site   https://doi.org/10.1073/pnas.1917595117
    Acrosin is essential for sperm penetration through the zona pellucida in hamsters.プレス発表 (Japanese)

  51. Ogura A. How to improve mouse cloning. Theriogenology 150: 215-220, 2020
  52. Matoba S, Miura K, Hirose M, Shiura H, Kohda T, Nakamuta N, Ogura A.  Paternal knockout of Slc38a4/SNAT4 causes placental hypoplasia associated with intrauterine growth restriction in mice. Proc Natl Acad Sci U S A. PNAS Site https://www.pnas.org/content/116/42/21047/ Paternal knockout of Slc38a4/SNAT4 causes placental hypoplasia associated with intrauterine growth restriction in mice.プレス発表 (Japanese)
  53. Fulka H, Ogura A, Loi P, Fulka, Jr. J.  Dissecting the role of the germinal vesicle nuclear envelope and soluble content in the process of somatic cell remodeling and reprogramming.J Reprod Dev 65: 433-441, 2019
  54. Mochida K, Hasegawa A, Ogonuki N, Inoue K, Ogura A.  Early production of offspring by in vitro fertilization using first-wave spermatozoa from prepubertal male mice. 
    J Reprod Dev  65: 467-473, 2019

  55. Ogonuki N, Abe Y, Kurotaki YK, Nakao K, Aiba A, Sasaki E, Ogura A. Birth of a marmoset following injection of elongated spermatid from a prepubertal male. Mol Reprod Dev 86:928-930, 2019
  56. Miura K, Harikae K, Nakaguchi M, Imaimatsu K, Hiramatsu R, Tomita A, Hirate Y, Kanai-Azuma M, Kurohmaru M, Ogura A, Kanai Y. Molecular and genetic characterization of partial masculinization in embryonic ovaries grafted into male nude mice. PLoS One 14:e0212367, 2019
  57. Morimoto H, Kanastu-Shinohara M, Ogonuki N, Kamimura S, Ogura A, Yabe-Nishimura C, Mori Y, Morimoto T, Watanabe S, Otsu K, Yamamoto T, Shinohara T. ROS amplification drives mouse spermatogonial stem cell self-renewal. Life Sci Alliance 2: e201900374, 2019
  58. Matsuda M, Ono R, Iyoda T, Endo T, Iwasaki M, Tomizawa-Murasawa M, Saito Y, Kaneko A, Shimizu K, Yamada D, Ogonuki N, Watanabe T, Nakayama M, Koseki Y, Kezuka-Shiotani F, Hasegawa T, Yabe H, Kato S, Ogura A, Shultz LD, Ohara O, Taniguchi M, Koseki H, Fujii SI, Ishikawa F. Human NK cell development in hIL-7 and hIL-15 knock-in NOD/SCID/IL2rgKO mice. Life Sci Alliance 2: e201800195, 2019
  59. Binbin L, Maekawa T, Yoshida K, Ly N, Inoue K, Hasegawa A, Chatton B, Ogura A, Ishii S.  Telomere shortening by transgenrational transmission of TNF-α-induced TERRA via ATF7. Nuc Acid Res 47:283-298, 2019.
  60. Inoue K,  Matoba S, Ogura A. Somatic cell nuclear transfer in mice: Basic protocol and its modification for correcting X chromosome inactivation status. Methods Mol Biol 1861:55-65, 2018. doi: 10.1007/978-1-4939-8766-5_5.
  61. Hirose M,  Ogura A. The golden (Syrian) hamster as a model for the study of reproductive biology: Past, present, and future. Reprod Med Biol 18:34-39, 2018
  62. Hirose M, Hada M, Kamimura S, Matoba S, Honda A, Motomura K, Ogonuki N, Shawki HH, Inoue K, Takahashi S, Ogura A. Aberrant imprinting in mouse trophoblast stem cells established from somatic cell nuclear transfer-derived embryos. Epigenetics 13:693-703, 2018
  63. Matoba S, Wang H, Jiang L, Lu F, Iwabuchi KA, Wu X, Inoue K, Yang L, Press W, Lee JT, Ogura A, Shen L, Zhang Y. Loss of H3K27me3 Imprinting in Somatic Cell Nuclear Transfer Embryos Disrupts Post-Implantation Development. Cell Stem Cell 23:343-354, 2018 Loss of H3K27me3 Imprinting in Somatic Cell Nuclear Transfer Embryos Disrupts Post-Implantation Development.プレス発表 (Japanese)
  64. Matoba S, Zhang Y. Somatic cell nuclear transfer reprogramming: mechanisms and applications. Cell Stem Cell DOI: https://doi.org/10.1016/j.stem.2018.06.018
  65. Miura K, Matoba S, Ogonuki N, Namiki T, Ito J, Kashiwazaki N, Ogura A. Application of auxin-inducible degron technology to mouse oocyte activation with PLCζ. J Reprod Dev 64:319-326, 2018
  66. Watanabe S, Kanatsu-Shinohara M, Ogonuki N, Matoba S, Ogura A, Shinohara T. In vivo genetic manipulation of spermatogonial stem cells and their microenvironment by adeno-associated viruses. Stem Cell Reports 10: 1551-1564, 2018
  67. Ogonuki N. Inoue H, Matoba S, Kurotaki YK, Kassai H, Abe Y, Sasaki E, Aiba A, Ogura A. Oocyte-activating capacity of fresh and frozen-thawed spermatids in the common marmoset (Callithrix jacchus). Mol Reprod Dev 85:376-386, 2018
  68. Shawki HH, Oishi H, Usui T, Kitadate Y, Basha WA, Abdellatif AM, Hasegawa K, Okada R, Mochida K, El-Shemy HA, Muratani M, Ogura A, Yoshida S, Takahashi S. MAFB is dispensable for the fetal testis morphogenesis and the maintenance of spermatogenesis in adult mice. PLoS One 13:e0190800, 2018. doi: 10.1371/journal.pone.0190800.
  69. Liu J, Mochida K, Hasegawa A, Inoue K, Ogura A. Identification of quantitative trait loci associated with the susceptibility of mouse spermatozoa to cryopreservation. J Reprod Dev 64:117-127, 2018.
  70. Hatanaka Y, Tsusaka T, Shimizu N, Morita K, Suzuki T, Machida S, Satoh M, Honda A, Hirose M, Kamimura S, Ogonuki N, Nakamura T, Inoue K, Hosoi Y, Dohmae N, Nakano T, Kurumizaka H, Matsumoto K, Shinkai Y, Ogura A. Histone H3 methylated at arginine 17 is essential for reprogramming the paternal genome in zygotes. Cell Rep 20: 2756-2765, 2017.Histone H3 methylated at arginine 17 is essential for reprogramming the paternal genome in zygotes.プレス発表 (Japanese)
  71. Shinohara T, Kazuki K, Ogonuki N, Morimoto H, Matoba S, Hiramatsu K, Honma K, Suzuki T, Hara T, Ogura A, Oshimura M, Kanatsu-Shinohara M, Kazuki Y. Transfer of a mouse artificial chromosome into spermatogonial stem cells generates transchromosomic mice. Stem Cell Rep 9: 1180-1191, 2017.
  72. Ogura A. Cloning Mice. Cold Spring Harb Protoc 2017(8):pdb.prot094425 2017. doi: 10.1101/pdb.prot094425.
  73. Hasegawa A, Mochida K, Ogonuki N, Hirose M, Tomishima T, Inoue K, Ogura A. Efficient and scheduled production of pseudopregnant female mice for embryo transfer by estrous cycle synchronization. J Reprod Dev 63: 539-545, 2017.
  74. Okuda K, Kobayashi S, Fukaya M, Watanabe A, Murakami T, Hagiwara M, Sato T, Ueno H, Ogonuki N, Komano-Inoue S, Manabe H, Yamaguchi M, Ogura A, Asahara H, Sakagami H, Mizuguchi M, Manabe T, Tanaka T. CDKL5 controls postsynaptic localization of GluN2B-containing NMDA receptors in the hippocampus and regulates seizure susceptibility. Neurobiol Dis 106: 158-170, 2017.
  75. Dong Y, Isono KI, Ohbo K, Endo TA, Ohara O, Maekawa M, Toyama Y, Ito C, Toshimori K, Helin K, Ogonuki N, Inoue K, Ogura A, Yamagata K, Kitabayashi I, Koseki H. EPC1/TIP60-mediated histone acetylation facilitates spermiogenesis in mice. Mol Cell Biol 37: e00082-17, 2017. doi: 10.1128/MCB.00082-17
  76. Honda A, Ogura A. Rabbit models for biomedical research revisited via genome editing approaches. J Reprod Dev 63: 435-438, 2017.
  77. Inoue K, Hirose M, Inoue H, Hatanaka Y, Honda A, Hasegawa A, Mochida K, Ogura A. The rodent-specific microRNA cluster within the Sfmbt2 gene is imprinted and essential for placental development. Cell Rep 19: 949-956, 2017. doi: 10.1016/j.celrep.2017.04.018The rodent-specific microRNA cluster within the Sfmbt2 gene is imprinted and essential for placental development.プレス発表 (Japanese)
  78. Kaminuma O, Katayama K, Inoue K, Saeki M, Nishimura T, Kitamura N, Shimo Y, Tofukuji S, Ishida S, Ogonuki N, Kamimura S, Oikawa M, Katoh S, Mori A, Shichijo M, Hiroi T, Ogura A. Hyper-reactive cloned mice generated by direct nuclear transfer of antigen-specific CD4+ T cells. EMBO Reports 18: 885-893, 2017. doi: 10.15252/embr.201643321プレス発表 (Japanese)
  79. Honda A, Kawano Y, Izu H, Choijookhuu N, Honsho K, Nakamura T, Yabuta Y, Yamamoto T, Takashima Y, Hirose M, Sankai T, Hishikawa Y, Ogura A, Saitou M. Discrimination of stem cell status after subjecting cynomolgus monkey pluripotent stem cells to naïve conversion. Sci Rep 7:45285, 2017. DOI: 10.1038/srep45285プレス発表 (Japanese)
  80. Hirose M, Hasegawa A, Mochida K, Matoba S, Hatanaka Y, Inoue K, Goto T, Kaneda H, Yamada I, Furuse T, Abe K, Uenoyama Y, Tsukamura H, Wakana S, Honda A, Ogura A. CRISPR/Cas9-mediated genome editing in wild-derived mice: generation of tamed wild-derived strains by mutation of the a (nonagouti) gene. Sci Rep 7:42476, 2017. doi: 10.1038/srep42476CRISPR/Cas9-mediated genome editing in wild-derived mice: generation of tamed wild-derived strains by mutation of the a (nonagouti) gene.プレス発表 (Japanese)
  81. Nakasuji T, Ogonuki N, Chiba T, Kato T, Shiozawa K, Yamatoya K, Tanaka H, Kondo T, Miyado K, Miyasaka N, Kubota T, Ogura A, Asahara H. Complementary critical functions of Zfy1 and Zfy2 in mouse spermatogenesis and reproduction. PLoS Genet 13(1):e1006578, 2017Complementary critical functions of Zfy1 and Zfy2 in mouse spermatogenesis and reproduction.プレス発表 (Japanese)
  82. Mochida K, Hasegawa A, Ogura A. Recent technical breakthroughs for ARTs in mice (Review). J Mam Ova Res 34: 13-21, 2017 DOI: 10.1274/jmor.34.13
  83. Watanabe S, Kanatsu-Shinohara M, Ogonuki N, Matoba S, Ogura A, Shinohara T. Adeno-associated virus-mediated delivery of genes to mouse spermatogonial stem cells. Biol Reprod 96: 221-231, 2017.
  84. Ogura A. Development of reproductive engineering techniques at the RIKEN BioResource Center (2016 JALAS Ando-Tajima Award). Exp Anim 66: 1-16, 2017. doi: 10.1538/expanim.16-007
  85. Kanatsu-Shinohara M, Tanaka T, Ogonuki N, Ogura A, Morimoto H, Cheng PF, Eisenman RN, Trumpp A, Shinohara T. Myc/Mycn-mediated glycolysis enhances mouse spermatogonial stem cell self-renewal. Genes Dev 30:2637-2648, 2016.
  86. Kojima-Kita K, Kuramochi-Miyagawa S, Nagamori I, Ogonuki N, Ogura A, Hasuwa H, Akazawa T, Inoue N, Nakano T. MIWI2 as an effector of DNA methylation and gene silencing in embryonic male germ cells. Cell Rep 16: 2819-2828, 2016.
  87. Inoue H, Ogonuki N, Hirose M, Hatanaka Y, Matoba S, Chuma S, Kobayashi K, Wakana S, Noguchi J, Inoue K, Tanemura K, Ogura A. Mouse D1Pas1, a DEAD-box RNA helicase, is required for the completion of first meiotic prophase in male germ cells.Biochem Biophys Res Comm 478: 592-598, 2016
  88. Kanemori Y, Koga Y, Sudo M, Kang W, Kashiwabara S, Ikawa M, Hasuwa H, Nagashima K, Ishikawa Y, Ogonuki N, Ogura A, Baba T. Biogenesis of sperm acrosome is regulated by pre-mRNA alternative splicing of Acrbp in the mouse. Proc Natl Acad Sci USA 113:E3696-3705, 2016.
  89. Motomura K, Oikawa M, Hirose M, Honda A, Togayachi S, Miyoshi H, Ohinata Y, Sugimoto M, Abe K, Inoue K, Ogura A. Cellular dynamics of mouse trophoblast stem cells: Identification of a persistent stem cell type. Biol Reprod 94:122, 2016.
  90. Loi P, Iuso D, Czernik M, Ogura A. A new, dynamic era for somatic cell nuclear transfer? Trends in Biotechnology 34: 791-797, 2016.
  91. Komeya M, Kimura H, Nakamura H, Yokonishi T, Sato T, Kojima K, Hayashi K, Katagiri K, Yamanaka H, Sanjo H, Yao M, Kamimura S, Inoue K, Ogonuki N, Ogura A, Fujii T, Ogawa T. Long-term ex vivo maintenance of testis tissues producing fertile sperm in a microfluidic device. Sci Rep 6:21472, 2016
  92. Uchio-Yamada K, Monobe Y, Akagi K, Yamamoto Y, Ogura A, Manabe N. Tensin2-deficient mice on FVB/N background develop severe glomerular disease. J Vet Med Sci 78: 811-818, 2016
  93. Motomura K, Inoue K, Ogura A. Selection of accurate reference genes in mouse trophoblast stem cells for reverse transcription–quantitative polymerase chain reaction. J Reprod Dev 62:311-315, 2016.
  94. Hasegawa A, Mochida K, Inoue H, Noda Y, Endo T, Watanabe G, Ogura A. High-yield superovulation in adult mice by anti-inhibin serum treatment combined with estrous cycle synchronization. Biol Reprod 94: 1-8, 2016.
  95. Hatanaka Y,  Inoue K, Oikawa M, Kamimura S, Ogonuki N, Kodam E, Ohkawa Y, Tsukada Y, Ogura A. Histone chaperone CAF-1 mediates repressive histone modifications to protect preimplantation mouse embryos from endogenous retrotransposon. Proc Natl Acad Sci USA 112:14641-14646, 2015.
    Histone chaperone CAF-1 mediates repressive histone modifications to protect preimplantation mouse embryos from endogenous retrotransposon.ABSTRACTHistone chaperone CAF-1 mediates repressive histone modifications to protect preimplantation mouse embryos from endogenous retrotransposon.プレス発表 (Japanese)
  96. Inoue K, Ogura A. In quest of genomic treasure. J Reprod Dev 61: 489-493, 2015.
  97. Sato T, Sakuma T, Yokonishi T, Katagiri K, Kamimura S, Ogonuki N, Ogura A, Yamamoto T, Ogawa T. Genome Editing in Mouse Spermatogonial Stem Cell Lines Using TALEN and Double-Nicking CRISPR/Cas9. Stem Cell Reports 5: 75-82, 2015.
  98. Kuroki S, Akiyoshi M, Ideguchi K, Kitano S, Miyachi H, Hirose M, Mise N, Abe K, Ogura A, Tachibana M. Development of a general-purpose method for cell purification using Cre/loxP-mediated recombination. Genesis 53:387-393, 2015.
  99. Inoue K, Oikawa M, Kamimura S, Ogonuki N, Nakamura T, Nakano T, Abe K, Ogura A. Trichostatin A specifically improves the aberrant expression of transcription factor genes in embryos produced by somatic cell nuclear transfer. Sci Rep 5:10127, 2015.
  100. Itou D, Shiromoto Y, Shin-Ya Y, Ishii C, Nishimura T, Ogonuki N, Ogura A, Hasuwa H, Fujihara Y, Kuramochi-Miyagawa S, Nakano T. Induction of DNA methylation by artificial piRNA production in male germ cells. Curr Biol 25:901-906, 2015.
  101. Ohtsuka M, Miura H, Mochida K, Hirose M, Hasegawa A, Ogura A, Mizutani R, Kimura M, Isotani A, Ikawa M, Sato M, Gurumurthy CB. One-step generation of multiple transgenic mouse lines using an improved Pronuclear Injection-based Targeted Transgenesis (i-PITT). BMC Genomics 6:274, 2015.
  102. Kurotaki YK, Hatanaka Y, Kamimura S, Oikawa M, Inoue H, Ogonuki N, Inoue K, Ogura A. Impaired active DNA demethylation in zygotes generated by round spermatid injection. Hum Reprod 30:1178-1187, 2015
  103. Mizutani E, Oikawa M, Kassai H, Inoue K, Shiura H, Hirasawa R, Kamimura S, Matoba S, Ogonuki N, Nagatomo H, Abe K, Wakayama T, Aiba A, Ogura A. Generation of cloned mice from adult neurons by direct nuclear transfer. Biol Reprod 92:81, 2015
  104. Takashima S, Kanatsu-Shinohara S, Tanaka S, Inoue K, Ogonuki N, Jijiwa M, Takahashi M, Ogura A, Shinohara T. Functional identification of mouse spermatogonial stem cells with distinct self-renewal properties. Stem Cell Rep 4:489-502, 2015. Functional identification of mouse spermatogonial stem cells with distinct self-renewal properties.プレス発表 (Japanese)
  105. Sugimoto M, Kondo M, Koga Y, Shiura H, Ikeda R, Hirose M, Ogura A, Murakami A, Yoshiki a, Chuva de Sousa Lopes SM, Abe K. A Simple and Robust Method for Establishing Homogeneous Mouse Epiblast Stem Cell Lines by Wnt Inhibition. Stem Cell Rep 4:744-757, 2015.
  106. Honsho K, Hirose M, Hatori M, Yasmin L, Izu H, Matoba S, Togayachi S, Miyoshi H, Sankai T, Ogura A, Honda A. Naïve-like conversion enhances the difference in innate in vitro differentiation capacity between rabbit ES cells and iPS cells. J Reprod Dev 61:13-19, 2015.
  107. Honda A, Hirose M, Sankai T, Yasmin L, Yuzawa K, Honsho K, Izu H, Iguchi A, Ikawa M, Ogura A. Single-step generation of rabbits carrying a targeted allele of Tyrosinase gene using CRISPR/Cas9. Exp Anim 64:31-37, 2015.
  108. Mochida K, Hasegawa A, Otaka N, Hama D, Furuya T, Yamaguchi M, Ichikawa E, Ijuin M, Taguma K, Hashimoto M, Takashima R, Kadota M, Hiraiwa N, Mekada K, Yoshiki A, Ogura A. Devising Assisted Reproductive Technologies for Wild-Derived Strains of Mice: 37 Strains from Five Subspecies of Mus musculus. PLoS One 9: e114305, 2014.
  109. Kamimura S, Hatanaka, Y, Hirasawa,R Matsumoto K, Oikawa, M, Lee J, Matoba S, Mizutani E, Ogonuki N, Inoue K, Kohda T, Ishino F, Ogura A. Establishment of paternal genomic imprinting in mouse prospermatogonia analyzed by nuclear transfer. Biol Reprod 91: 120, 1–12, 2014.
  110. Kanatsu-Shinohara M, Ogonuki N, Matoba S, Morimoto H, Ogura A, and Shinohara T. Improved serum- and feeder-free culture of mouse spermatogonial stem cells. Biol Reprod 91: 88, 1–11, 2014.
  111. Yokonishi T, Sato T, Komeya M, Katagiri K, Kubota Y, Nakabayashi K, Hata K, Inoue K, Ogonuki N, Ogura A, Ogawa T. Offspring production with sperm grown in vitro from cryopreserved testis tissues. Nat Commun 5:4320, 2014. doi: 10.1038/ncomms5320
  112. Hatori M, Shimozawa N, Yasmin L, Suemori H, Nakatsuji N, Ogura A, Yagami K, Sankai T. Role of retinoic acid and fibroblast growth factor 2 in neural differentiation from cynomolgus monkey (Macaca fascicularis) embryonic stem cells. Comparative Medicine 64: 140-147, 2014.
  113. Hasegawa A, Mochida K, Tomishima T, Inoue K, Ogura A. Microdroplet in vitro rertilization can reduce the number of spermatozoa necessary for fertilizing oocytes. . J Reprod Dev 60: 187-193, 2014.
  114. Shinagawa T, Takagi T, Tsukamoto D, Tomaru C, Huynh LM, Sivaraman P, Kumarevel T, Inoue K, Nakato R, Katou Y, Sado T, Takahashi S, Ogura A, Shirahige K, Ishii, S. Histone variants enriched in oocytes enhance reprogramming to induced pluripotent stem cells. Cell Stem Cell 14: 217-227, 2014.
  115. Takasaki N, Tachibana K, Ogasawara S, Matsuzaki H, Hagiuda J, Ishikawa H, Mochida K, Inoue K, Ogonuki N, Ogura A, Noce T, Ito C, Toshimori K, Narimatsu H. A heterozygous mutation of GALNTL5 affects male infertility with impairment of sperm motility. Proc Natl Acad Sci USA 111: 1120-1125, 2014.A heterozygous mutation of GALNTL5 affects male infertility with impairment of sperm motility.プレス発表 (Japanese)
  116. Khalaj M, Abbasi A, Yamanishi H, Akiyama K, Wakitani S, Kikuchi S, Hirose M, Yuzuriha M, Magari M, Degheidy HA, Abe K, Ogura A, Hashimoto H, Kunieda T. A missense mutation in Rev7 disrupts formation of Polζ, impairing mouse development and repair of genotoxic-agent-induced DNA lesions. J Biol Chem 289: 3811-3824, 2014.
  117. Oikawa M, Inoue K, Shiura H, Matoba S, Kamimura S, Hirose M, Mekada K, Yoshiki A, Tanaka A, Abe K, Ishino F, Ogura A. Understanding the X chromosome inactivation cycle in mice: A comprehensive view provided by nuclear transfer. Epigenetics 9: 204–211, 2014.
  118. Nagai A, Hattori T, Hirose M, Ogura A, Nozaki K, Aizawa M, Yamashita K. Mouse embryonic stem cells cultured under serum- and feeder-free conditions maintain their self-renewal capacity on hydroxyapatite. Materials Science and Engineering C 34: 214–220, 2014.
  119. Udagawa O, Ito C, Ogonuki N, Sato H, Lee S, Tripuvanuntakul P, Ichi I, Uchida Y, Nishimura T, Murakami M, Ogura A, Inoue T, Toshimori K, Arai H. Oligo-astheno-teratozoospermia in mice lacking ORP4, a sterol-binding protein in the OSBP-related protein family. Genes Cells 19: 13-27, 2014.
  120. Okae H, Matoba S, Nagashima T, Mizutani E, Inoue K, Ogonuki N, Chiba H, Funayama R, Tanaka S, Yaegashi N, Nakayama K, Sasaki H, Ogura A, Arima T. RNA sequencing-based identification of aberrant imprinting in cloned mice. Hum Mol Genet 23: 992-1001, 2014.
  121. Kuroki S, Matoba S, Akiyoshi M, Matsumura Y, Miyachi H, Mise N, Abe K, Ogura A, Wilhelm D, Koopman P, Nozaki M, Kanai Y, Shinkai Y, Tachibana M. Epigenetic regulation of mouse sex determination by the histone demethylase Jmjd1a. Science 341: 1106-1109, 2013.
  122. Akiyama K, Noguchi J, Hirose M, Kajita S, Katayama K, Khalaj M, Tsuji T, Ogura A, Kunieda T. A mutation in the nuclear pore complex gene Tmem48 causes gametogenesis defects in skeletal fusions with sterility (sks) mice. J Biol Chem. 288:31830-31841, 2103.
  123. Uchio-Yamada K, Sawada K, Tamura K, Katayama S, Monobe Y, Yamamoto Y, Ogura A, Manabe N. Tenc1-Deficient Mice Develop Glomerular Disease in a Strain-Specific Manner. Nephron Exp Nephrol 123: 22-33, 2013.
  124. Hirasawa R, Matoba S, Inoue K, Ogura A. Somatic donor cell type correlates with embryonic, but not extra-embryonic, gene expression in postimplantation cloned embryos. PLoS One 8: e76422, 2013.
  125. Takashima S, Hirose M, Ogonuki N, Ebisuya M, Inoue K, Kanatsu-Shinohara M, Tanaka T, Nishida E, Ogura A, Shinohara T. Regulation of pluripotency in male germline stem cells by Dmrt1.Genes Dev 27: 1949-1958, 2013.
  126. Honda A, Hatori M, Hirose M, Honda C, Izu H, Inoue K, Hirasawa R, Matoba S, Togayachi S, Miyoshi H, Ogura A. Naive-like conversion overcomes the limited differentiation capacity of induced pluripotent stem cells. J Biol Chem 288(36):26157-26166, 2013.ヒト型iPS細胞の品質を改善することに成功のプレス発表PDFプレス発表(Japanese)
    Naive-like conversion overcomes the limited differentiation capacity of induced pluripotent stem cells. ABSTRACT

  127. Kushiyama A, Sakoda H, Oue N, Okubo M, Nakatsu Y, Ono H, Fukushima T, Kamata H, Nishimura F, Kikuchi T, Fujishiro M, Nishiyama K, Aburatani H, Kushiyama S, Iizuka M, Taki N, Encinas J, Sentani K, Ogonuki N, Ogura A, Kawazu S, Yasui W, Higashi Y, Kurihara H, Katagiri H, Asano T. Resistin-like molecule β is abundantly expressed in foam cells and is involved in atherosclerosis development. Arterioscler Thromb Vasc Biol 33: 1986-1993, 2013.
  128. Funaki T, Kon S, Tanabe K, Natsume W, Sato S, Shimizu T, Yoshida N, Wong WF, Ogura A, Ogawa T, Inoue K, Ogonuki N, Miki H, Mochida K, Endoh K, Yomogida K, Fukumoto M, Horai R, Iwakura Y, Ito C, Toshimori K, Watanabe T, Satake M. The Arf GAP SMAP2 is necessary for organized vesicle budding from the trans-Golgi-network and subsequent acrosome Formation in Spermiogenesis. Mol Biol Cell. 24: 2633-2644, 2013.
  129. Morimoto H, Iwata K, Ogonuki N, Inoue K, Ogura A, Kanatsu-Shinohara M, Morimoto T, Yabe-Nishimura C, Shinohara T. ROS are required for mouse spermatogonial stem cell self-renewal. Cell Stem Cell 12: 774–786, 2013.   『活性酸素の精子幹細胞に対する増殖促進作用を解明』プレス発表プレス発表(Japanese)
  130. Fujiwara Y, Ogonuki N, Inoue K, Ogura A, Handel MA, Noguchi J, Kunieda T. t-SNARE Syntaxin2 (STX2) is implicated in intracellular transport of sulfoglycolipids during meiotic prophase in spermatogenesis. Biol Reprod 88: 141, 1–9, 2013
  131. Kamimura S, Inoue K, Ogonuki N, Hirose M, Oikawa M, Yo M, Ohara O, Miyoshi H, Ogura A. Mouse cloning using a drop of peripheral blood. Biol Reprod 89 24, 1-6, 2013. 一滴の血液からクローンマウスを誕生させることに成功プレス発表(Japanese)
    Mouse cloning using a drop of peripheral blood. ABSTRACT

  132. Shiura H, Ikeda R, Lee J, Sato T, Ogonuki N, Hirose M, Ogura A, Ogawa T, Abe K. Generation of a novel germline stem cell line expressing a germline-specific reporter in the mouse. Genesis 51: 498-505, 2013.
  133. Oikawa M, Matoba S, Inoue K, Kamimura S, Hirose M, Ogonuki N, Shiura H, Sugimito M, Abe K, Ishino F, Ogura A. RNAi-mediated knockdown of Xist does not rescue the impaired development of female cloned mouse embryos. J Reprod Dev 59: 231-237, 2013.
  134. Mochida K,Hasegawa A, Li M-W, Fray MD, Kito S, Vallelunga JM, Lloyd KCK, Yoshiki A, Obata Y, Ogura A. High osmolality vitrification: A new method for the simple and temperature-permissive cryopreservation of mouse embryos. PLoS One 8: e49316, 2013
  135. Sugimoto M, Kondo M, Hirose M, Suzuki M, Mekada K, Abe T, Kiyonari H, Ogura A, Takagi N, Artzt K, Abe K. Molecular identification of t(w5): Vps52 promotes pluripotential cell differentiation through cell-cell interactions. Cell Rep doi:pii:S2211-1247(12)00340-3. 10.1016/j.celrep.2012.10.004.
  136. Mizutani E, Ogura A, Wakayama T. Nuclear transfer in the mouse oocyte. Methods Mol Biol 957:285-300, 2012.
  137. Kanatsu-Shinohara M, Inoue K, Takashima S, Takehashi M, Ogonuki N, Morimoto H, Nagasawa T, Ogura A, Takashi Shinohara. Reconstitution of mouse spermatogonial stem cell niches in culture. Cell Stem Cell 11:567-578, 2012.
  138. Sato T, Yokonishi T, Komeya M, Katagiri K, Kubota Y, Matoba S, Ogonuki N, Ogura A, Yoshida S, Ogawa T. Testis tissue explantation cures spermatogenic failure in c-Kit ligand mutant mice. Proc Natl Acad Sci USA 109:16934-16938, 2012.

  139. Jin B, Mochida K, Ogura A, Koshimoto C, Matsukawa K, Kasai M, Edashige K. Equilibrium vitrification of mouse embryos at various developmental stages. Mol Reprod Dev 79: 785-794, 2012.
  140. Ogura A, Inoue K, Wakayama T. Recent advancements in cloning by somatic cell nuclear transfer. Philos Trans R Soc Lond B Biol Sci 368: 20110329. http://dx.doi.org/10.1098/rstb.2011.0329

  141. Nakamura T, Liu Y-J, Nakashima H, Umehara H, Inoue K, Matoba S, Tachibana M, Ogura A, Shinkai Y, Nakano T. PGC7 binds histone H3K9me2 to protect against conversion of 5mC to 5hmC in early embryos. Nature 486, 415-419, doi:10.1038/nature11093, 2012.
     ABSTRACT

  142. Hasegawa A, Mochida K, Matoba S, Yonezawa K, Ohta A, Watanabe G, Taya K, Ogura A. Efficient production of offspring from Japanese wild-derived strains of mice (Mus musculus molossinus) by improved assisted reproductive technologies. Biol Reprod. 86(5):167,1-7, 2012.
    Efficient production of offspring from Japanese wild-derived strains of mice (Mus musculus molossinus) by improved assisted reproductive technologies. ABSTRACT(OPEN ACCESS ARTICLE)
    Comment in

  143. Kohama C, Kato H, Numata K, Hirose M, Takemasa T, Ogura A, Kiyosawa H. ES cell differentiation system recapitulates the establishment of imprinted gene expression in a cell-type-specific manner. Hum Mol Genet 21: 1391-1401, 2012.
    ES cell differentiation system recapitulates the establishment of imprinted gene expression in a cell-type-specific manner. ABSTRACT

  144. Hasegawa A, Yonezawa K, Ohta A, Mochida K, Ogura A. Optimization of a protocol for cryopreservation of mouse spermatozoa using cryotubes. J Reprod Dev. 58:156-161, 2012
  145. Matoba S, Inoue K, Kohda T, Sugimioto M, Mizutani E, Ogonuki N, Nakamura T, Abe K, Nakano T, Ishino F, and Ogura A. RNAi-mediated knockdown of Xist can rescue the impaired postimplantation development of cloned mouse embryos. Proc Natl Acad Sci USA 108; 20621-20626, 2011
    RNAi-mediated knockdown of Xist can rescue the impaired postimplantation development of cloned mouse embryos. ABSTRACT(OPEN ACCESS ARTICLE)RNAi-mediated knockdown of Xist can rescue the impaired postimplantation development of cloned mouse embryos.プレス発表 (Japanese)
    Comment in

  146. Sato T, Katagiri K, Yokonishi T, Inoue K, Ogonuki N, Matoba S, Ogura A, Ogawa T. In vitro differentiation of germline stem cells into fertile sperm in testis tissue explants. Nature Commun 2:472, 2011. doi: 10.1038/ncomms1478
    In vitro differentiation of germline stem cells into fertile sperm in testis tissue explants. ABSTRACT

  147. Kohda T, Ogonuki N, Inoue K, Furuse T, Kaneda H, Suzuki T, Kaneko-Ishino T, Wakayama T, Wakana S, Ogura A, Ishino F. Intracytoplasmic sperm injection induces transcriptome perturbation without any transgenerational effect. Biochem Biophys Res Commun. 410: 282-288, 2011
    Intracytoplasmic sperm injection induces transcriptome perturbation without any transgenerational effect. ABSTRACT

  148. Sato T, Katagiri K, Gohbara A, Inoue K, Ogonuki N, Ogura A, Kubota Y, & Ogawa T. In vitro production of functional sperm in cultured neonatal mouse testes. Nature 471: 504–507, 2011
    In vitro production of functional sperm in cultured neonatal mouse testes. ABSTRACT

  149. Mochida K, Hasegawa A, Taguma K, Yoshiki A, Ogura A. Cryopreservation of mouse embryos by ethylene glycol-based vitrification. Journal of Visualized Experiments 57: e3155, 2011.
     ABSTRACT(OPEN ACCESS ARTICLE)

  150. Ogonuki N, Inoue K, Ogura A. Birth of normal mice following round spermatid injection without artificial oocyte activation. J Reprod Dev 57: 534-538, 2011
    Birth of normal mice following round spermatid injection without artificial oocyte activation. ABSTRACT(OPEN ACCESS ARTICLE)

  151. Fulka H, Hirose M, Inoue K, Ogonuki N, Wakisaka N, Matoba S, Ogura A, Mosko T, Kott T Fulka, J. Jr. Production of mouse embryonic stem cell lines from maturing oocytes by direct conversion of meiosis into mitosis. Stem Cells 29: 517–527, 2011
    Production of mouse embryonic stem cell lines from maturing oocytes by direct conversion of meiosis into mitosis. ABSTRACT

  152. Matoba S, Ogura A. Generation of functional oocytes and spermatids from fetal primordial germ cells after ectopic transplantation in adult animals. Biol. Reprod. 84: 631-838, 2011
    Generation of functional oocytes and spermatids from fetal primordial germ cells after ectopic transplantation in adult animals. ABSTRACT(OPEN ACCESS ARTICLE)
        Comment in

  153. Kanatsu-Shinohara M, Inoue K, Ogonuki N, Morimoto H, Ogura A, Shinohara T. Serum- and Feeder-Free Culture of Mouse Germline Stem Cells. Biol. Reprod. 84 :97-105, 2011.
    Serum- and Feeder-Free Culture of Mouse Germline Stem Cells. ABSTRACT

  154. Mochida K, Ogura A. Cryopreservation of embryos in laboratory species (review). J. Mamm. Ova. Res. C 27: 87-92, 2010.
    Cryopreservation of embryos in laboratory species (review). ABSTRACT(OPEN ACCESS ARTICLE)

  155. Inoue K, Kohda T, Sugimoto M, Sado T, Ogonuki N, Matoba S, Shiura H, Ikeda R, Mochida K, Fujii T, Sawai K, Otte AP, Tian XC, Yang X, Ishino F, Abe K, Ogura A. Impeding Xist expression from the active X chromosome improves mouse somatic cell nuclear transfer. Science 330: 496-499, 2010.
    Impeding Xist expression from the active X chromosome improves mouse somatic cell nuclear transfer.ABSTRACT   REPRINT (with permission from Science[www.aaas.org])Impeding Xist expression from the active X chromosome improves mouse somatic cell nuclear transfer.プレス発表 (Japanese)

  156. Honda A, Hirose M, Hatori M, Matoba S, Miyoshi H, Inoue K, Ogura A. Generation of induced pluripotent stem cells in rabbits: potential experimental models for human regenerative medicine. J Biol Chem, 285: 31362-31369, 2010.
    Generation of induced pluripotent stem cells in rabbits: potential experimental models for human regenerative medicine. ABSTRACT(OPEN ACCESS ARTICLE)

  157. Ogonuki N, Mori M, Shinmen A, Inoue K, Mochida K, Ohta A, Ogura A. The effect on intracytoplasmic sperm injection outcome of genotype, male germ cell stage and freeze-thawing in mice. PLoS ONE, 5(6): e11062. doi:10.1371/journal.pone.0011062
    The effect on intracytoplasmic sperm injection outcome of genotype, male germ cell stage and freeze-thawing in mice. ABSTRACT(OPEN ACCESS ARTICLE)

  158. Goto M, Shimada K, Sato A, Takahashi E, Fukasawa T, Takahashi T, Ohka S, Taniguchi T, Honda E, Nomoto A, Ogura A, Kirikae T, Hanaki KI.
    Rapid detection of Pseudomonas aeruginosa in mouse feces by colorimetric loop-mediated isothermal amplification. Microbiol Methods, 81: 247-52, 2010

  159. Hayashi Y, Furue MK, Tanaka S, Hirose M, Wakisaka N, Danno H, Ohnuma K, Oeda S, Aihara Y, Shiota K, Ogura A, Ishiura S, Asashima M.
    BMP4 induction of trophoblast from mouse embryonic stem cells in defined culture conditions on laminin. In Vitro Cell Dev Biol Anim, 46: 416-30, 2010

  160. Jin B, Mochida K, Ogura A, Hotta E, Kobayashi Y, Ito K, Egawa G, Seki S, Honda H, Edashige K, Kasai M. Equilibrium vitrification of mouse embryos. Biol Reprod, 82: 444-450, 2010
  161. Kanatsu-Shinohara M, Ogonuki N, Miki H, Inoue K, Morimoto H, Ogura A, Shinohara T. Genetic influences in mouse spermatogonial stem cell self-renewal. J Reprod. Dev, 56: 145-153, 2009
  162. Inoue K, Ogonuki N, Mekada K, Yoshiki A, Sado T, Ogura A. Sex-reversed somatic cell cloning in the mouse. J Reprod Dev, 55: 566-569, 2009
  163. Taguma K, Nakamura C, Ozaki A, Suzuki C, Hachisu A, Kobayashi K, Mochida K, Ogura A, Kaneda H, Wakana S. A practical novel method for ensuring stable capacitation of spermatozoa from cryopreserved C57BL/6J sperm suspension. Exp Anim, 58: 395-401, 2009
  164. Miki H, Wakisaka N, Inoue K, Ogonuki N, Mori M, Kim JM, Ohta A, Ogura A. Embryonic Rather than Extraembryonic Tissues Have More Impact on the Development of Placental Hyperplasia in Cloned Mice. Placenta, 30:543-546, 2009
  165. Kim J-M, Ogura A. Changes in allele-specific association of histone modifications at the imprinting control regions during mouse preimplantation development. Genesis, 47:611-616, 2009
  166. Ogonuki N, Inoue K, Hirose M, Miura I, Mochida K, Sato T, Mise N, Mekada K, Yoshiki A, Abe K, Kurihara H, Wakana S, Ogura A. A high-speed congenic strategy using first-wave male germ cells. PLoS One, 4(3): e4943. doi:10.1371/journal.pone.0004943.
  167. Honda A, Hirose M, Ogura A. Basic FGF and Activin/Nodal but not LIF signaling sustain undifferentiated status of rabbit embryonic stem cells. Exp Cell Res, 2033-2042, 2009
  168. Lee J, Kanatsu-Shinohara M, Ogonuki N, Miki H, Inoue K, Morimoto T, Morimoto H, Ogura A, Shinohara T. Heritable Imprinting Defect Caused by Epigenetic Abnormalities in Mouse Spermatogonial Stem Cells. Biol Reprod, 80: 518-527, 2009
  169. Goto M, Honda E, Ogura A, Nomoto A, Hanaki K-I. Colorimetric detection of loop-mediated isothermal amplification reaction by using hydroxy naphthol blue. BioTechniques, 46: 167-172, 2009
  170. Yoshiki A, Ike F, Mekada K, Kitaura Y, Nakata H, Hiraiwa N, Mochida K, Ijuin M, Kadota M, Murakami A, Ogura A, Abe K, Moriwaki K, Obata Y. The Mouse Resources at the RIKEN BioResource Center. Exp Anim, 58: 85-96, 2009
  171. Miki H, Hirose M, Ogonuki N, Inoue K, Kezuka F, Honda A, Mekada K, Hanaki K, Iwafune H, Yoshiki A, Ishino F, Ogura A. Efficient production of androgenetic embryos by round spermatid injection. Genesis, 47: 155-60, 2009
  172. Honda A, Hirose M, Inoue K, Hiura H, Miki H, Ogonuki N, Sugimoto M, Abe K, Kanatsu-Shinohara M, Kono T, Shinohara T, Ogura A. Large-scale production of growing oocytes in vitro from neonatal mouse ovaries. Int J Dev Biol, 53:605-613, 2009
  173. Shimozawa N, Sankai T, Ogura A. (Review) Reproductive rechnologies and the related studies in cynomolgus monkey. Mamm Ova Res, 25: 133-142, 2008
  174. Honda A, Hirose M, Inoue K, Ogonuki N, Miki H, Shimozawa N, Hatori M, Shimizu N, Murata T, Hirose H, Katayama K, Wakisaka N, Miyoshi H, Yokoyama KK, Sankai T, Ogura A. Stable ES cell lines in rabbits – potential small animal models for human ES cell research. Reprod Biomed Online, 17: 706-715, 2008.
  175. Wakisaka N, Inoue K, Ogonuki N, Miki H, Sekita Y, Hanaki K, Akatsuka K, Kaneko-Ishino T, Ishino F, Ogura A. Ultrastructure of placental hyperplasia in mice: Comparison of placental phenotypes with three different etiologies. Placenta, 29:753-759, 2008
  176. Nakamura T, Inoue K, Ogawa S, Umehara H, Ogonuki N, Miki H, Kimura T, Ogura A, Nakano T. Differential effects of Akt signaling on two types of nuclear reprogramming. Genes Cells, 13:1269-1277, 2008.
  177. Nakanishi T, Ishibashi N, Kubota H, Inoue K, Ogonuki N, Ogura A, Kashiwabara S, Baba T. Birth of normal offspring from mouse eggs activated by a phospholipase Cζ protein lacking three EF-hand domains. J Reprod Dev, 54:244-249, 2008
  178. Tachibana M, Terada Y, Ogonuki N, Ugajin T, Ogura A, Murakami T, Yaegashi N, Okamura K. Functional assessment of centrosomes of spermatozoa and spermatids microinjected into rabbit oocytes. Mol Reprod Dev, 76:270-277, 2009.
  179. Yamashita M., Honda A., Ogura A., Kashiwabara S., Fukami K., Baba T. Reduced fertility of mouse epididymal sperm lacking Prss21/Tesp5 is rescued by sperm exposure to uterine microenvironment. Genes Cells, 13:1001-1013, 2008.
  180. Kazuki Y, Hoshiya H, Kai Y, Abe S, Takiguchi M, Osaki M, Kawazoe S, Katoh M, Kanatsu-Shinohara M, Inoue K, Kajitani N, Yoshino T, Shirayoshi Y, Ogura A, Shinohara T, Barrett JC, Oshimura M. Correction of a genetic defect in multipotent germline stem cells using a human artificial chromosome. Gene Therapy, 15:617-624, 2008
  181. Kanatsu-Shinohara M, Lee J, Inoue K, Ogonuki N, Miki H, Toyokuni S, Ikawa M, Nakamura T, Ogura A, Shinohara T. Pluripotency of a single spermatogonial stem cell in mice. Biol Reprod, 78: 681-687, 2008
  182. Sekita Y, Wagatsuma H, Nakamura K, Ono R, Kagami M, Wakisaka N, Hino T, Suzuki-Migishima R, Kohda T, Ogura A, Ogata T, Yokoyama M, Kaneko-Ishino T, Ishino F. Role of retrotransposon-derived imprinted gene, Rtl1, in the feto-maternal interface of mouse placenta. Nat Genet, 40:243-248, 2008
  183. Yamagata K, Yamazaki T, Miki H, Ogonuki N, Inoue K, Ogura A and Tadashi Baba T. Centromeric DNA hypomethylation as an epigenetic signature discriminates between germ and somatic cell lineages. Dev. Biol., 312: 419-426, 2007
  184. Takehashi M, Kanatsu-Shinohara M, Miki H, Lee J, Kazuki Y, Inoue K, Ogonuki N, Toyokuni S, Oshimura M, Ogura A and Shinohara T. Production of knockout mice by gene targeting in multipotent germline stem cells. Dev. Biol., 312: 344-352, 2007
  185. Endoh K, Mochida K, Ogonuki N, Ohkawa M, Shinmen A, Ito M, Kashiwazaki N, Ogura A. The developmental ability of vitrified oocytes from different mouse strains assessed by parthenogenetic activation and intracytoplasmic sperm injection. J Reprod Dev., 53: 1199-1206, 2007
  186. Honda A, Hirose M, Hara K, Matoba S, Inoue K, Miki H, Hiura H, Kanatsu-Shinohara M, Kanai Y, Kono T, Shinohara T, Ogura A. Isolation, characterization, and in vitro and in vivo differentiation of putative thecal stem cells. Proc Natl Acad Sci USA, 104: 12389-12394, 2007
  187. Shinmen A, Honda A, Ohkawa M, Hirose M, Ogonuki N, Yuzuriha M, Miki H, Mochida K, Inoue K, Abe K, Ito M, Ogura A. Efficient production of intersubspecific hybrid mice and embryonic stem cells by intracytoplasmic sperm injection.Mol Reprod Dev, 74:1081-1088, 2007
  188. Yang X, Cheng T, Sung LY, Gao S, Shen H, Yu H, Song Y, Smith SL, Tuck DP, Inoue K, Weissman SM. Reply to "On the cloning of animals from terminally differentiated cells. Nat Genet, 39:137-138, 2007
  189. Inoue K, Noda S, Ogonuki N, Miki H, Inoue S, Katayama K, Mekada K, Miyoshi H, Ogura A. Differential developmental ability of embryos cloned from tissue-specific stem cells. Stem Cells, 25:1279-1285, 2007
  190. Lee J, Kanatsu-Shinohara M, Inoue K, Ogonuki N, Miki H, Toyokuni S, Kimura T, Nakano T, Ogura A, Shinohara T. Akt mediates self-renewal division of mouse spermatogonial stem cells.Development, 134: 1853-1859, 2007
  191. Takehashi M, Kanatsu-Shinohara M, Inoue K, Ogonuki N, Miki H, Toyokuni S, Ogura A, Shinohara T. Adenovirus-mediated gene delivery into mouse spermatogonial stem cells. Proc. Natl. Acad. Sci. USA, PNAS 2007 104 (8) 2596-2601, doi:10.1073/pnas.0609282104, 2007.
  192. Kita K, Watanabe T, Ohsaka K, Hayashi H, Kubota Y, Nagashima Y, Aoki I, Taniguchi H, Noce T, Inoue K, Miki H, Ogonuki N, Tanaka H, Ogura A, Ogawa T. Production of functional spermatids from mouse germline stem cells in ectopically reconstituted seminiferous tubules. Biol. Reprod., 76:55-62, 2007
  193. Kanatsu-Shinohara M, Inoue K, Ogonuki N, Miki H, Yoshida S, Toyokuni S, Lee J, Ogura A, Shinohara T. Leukemia inhibitory factor enhances formation of germ cell colonies in neonatal mouse testis culture. Biol. Reprod., 76: 55-62, 2007.
  194. Ogonuki N, Mochida K, Miki H, Inoue K, Fray M, Iwaki T, Moriwaki K, Obata Y, Morozumi K, Yanagimachi R, Ogura A. Spermatozoa and spermatids retrieved from frozen reproductive organs or frozen whole bodies of male mice can produce normal offspring. Proc. Natl. Acad. Sci. USA, 103: 13098-13103, 2006.
  195. Sung LY, Gao S, Shen H, Yu H, Song Y, Smith SL, Chang CC, Inoue K, Kuo L, Lian J, Li A, Tian XC, Tuck DP, Weissman SM, Yang X, Cheng T. Differentiated cells are more efficient than adult stem cells for cloning by somatic cell nuclear transfer. Nat Genet, 38:1323-1328, 2006
  196. Gotoh K, Inoue K, Ogura A, Oishi M. Intra-strain polymorphisms are detected but no genomic alteration is found in cloned mice. Biochem. Biophys. Res. Commun., 348: 166-169, 2006.
  197. Kishigami S, Wakayama S, Thuan NV, Ohta H, Mizutani E, Hikichi T, Bui H-T, Balbach S, Ogura A, Boiani M, Wakayama T. Production of cloned mice by somatic cell nuclear transfer.Nat. Protocols, 1: 125-138, 2006.
  198. Wakisaka-Saito N, Kohda T, Inoue K, Ogonuki N, Miki H, Hikichi T, Mizutani E, Wakayama T, Kaneko-Ishino T, Ogura A, Ishino F. Chorioallantoic placenta defects in cloned mice. Biochem. Biophys. Res. Commun., 349: 106-114, 2006.
  199. Kohda T, Ishino F, Ogura A. Expression of imprinted genes in cloned mice. Methods Mol. Biol., 348:237-246, 2006.
  200. Kanatsu-Shinohara M, Ikawa M, Takehashi M, Ogonuki N, Miki H, Inoue K, Kazuki Y, Lee J, Toyokuni S, Oshimura M, Ogura A, Shinohara T. Production of knockout mice by random or targeted mutagenesis in spermatogonial stem cells. Proc. Natl. Acad. Sci. USA, 103: 8018-8023, 2006.
  201. Kanatsu-Shinohara M, Inoue K, Miki H, Ogonuki N, Takehashi M, Morimoto T, Ogura A, Shinohara T. Clonal Origin of Germ Cell Colonies after Spermatogonial Transplantation in Mice. Biol. Reprod., 75: 68-74, 2006.
  202. Inoue K, Ogonuki N, Miki H, Hirose M, Noda S, Kim J-M, Aoki F, Miyoshi H, Ogura A. Inefficient reprogramming of the hematopoietic stem cell genome following nuclear transfer. J. Cell Sci., 119:1985-1991, 2006.
  203. Sekita Y, Wagatsuma H, Irie M, Kobayashi S, Kohda T, Matsuda J, Yokoyama M, Ogura A, Schuster-Gossler K, Gossler A, Ishino F, Kaneko-Ishino T. Aberrant regulation of imprinted gene expression in Gtl2lacz mice. Cytogenet Genome Res., 113: 223-229, 2006.
  204. Okada T, Ishii Y, Masujin K, Izawa N, Yasoshima A, Takano K, Matsuda J, Ogura A, Nakayama H, Kunieda T, Doi K. The critical roles of serum/glucocorticoid regulated kinase 3 (SGK3) in the hair follicle morphogenesis and homeostasis: the allelic difference provides novel insights into hair follicle biology. Am J Pathol, 168:1119-1133, 2006
  205. Miki H, Ogonuki N, Inoue K, Baba T, Ogura A. Improvement of cumulus-free oocyte maturation in vitro and its application to microinsemination with primary spermatocytes in mice. J. Reprod. Dev., 52: 239-248, 2006.
  206. Ono R, Nakamura K, Inoue K, Naruse M, Usami T, Wakisaka-Saito N, Hino T, Suzuki-Migishima R, Ogonuki N, Miki H, Kohda T, Ogura A, Yokoyama M, Kaneko-Ishino T, Ishino F. Deletion of Peg10, an imprinted gene acquired from a retrotransposon, causes early embryonic lethality. Nat. Genet., 38: 101-106, 2006.
  207. Kanatsu-Shinohara M, Inoue K, Lee J, Miki H, Ogonuki N, Toyokuni S, Ogura A, Shinohara T. Anchorage-independent growth of mouse male germline stem cells in vitro.Biol. Reprod., 74:522-529, 2006.
  208.  Inoue K,Wakao H, Ogonuki N, Miki H, Seino K, Nambu-Wakao R, Noda S, Miyoshi H, Koseki H, Taniguchi M, Ogura A. Generation of cloned mice by direct nuclear transfer from natural killer T cells. Curr. Biol., 15: 1114-1118, 2005
  209. Kohda T, Inoue K, Ogonuki N, Miki H, Naruse M, Kaneko-Ishino T, Ogura A, Ishino F. Variation in gene expression and aberrantly regulated 1 chromosome regions in cloned mice. Biol. Reprod., 73: 1302-1311, 2005
  210. Yamaguchi-Yamada M, Manabe N, Kiso M, Goto Y, Mori T, Sakata C, Anan S, Nagao M, Yamamoto Y, Ogura A. Dysfunction of erythropoetin-producing interstitial cells in the kidneys of ICR-derived glomerulonephritis(ICGN) mice. J. Vet. Med. Sci., 67: 891-899, 2005
  211. Ogura A, Ogonuki N, Miki H, Inoue K. Microinsemination and nuclear transfer using male germ cells. Int. Rev. Cytol., 246: 189-229, 2005
  212. Kanatsu-Shinohara M, Miki H, Inoue K, Ogonuki N, Toyokuni S, Ogura A, and Shinohara T. Long-term culture of mouse male germline stem cells under serum- or feeder-free conditions. Biol. Reprod., 72: 985-991, 2005
  213. Kanatsu-Shinohara M, Miki H, Inoue K, Ogonuki N, Toyokuni S, Ogura A, Shinohara T. Germline niche transplantation restores fertility in infertile mice. Hum. Reprod., 20: 2376-2382, 2005
  214. Tanemura K, Ogura A, Cheong C, Gotoh H, Matsumoto K, Sato E, Hayashi Y,Lee H.W, Kondo T. Dynamic rearrangement of telomeres during spermatogenesis in mice. Dev. Biol., 28: 196-207, 2005
  215. Kanatsu-Shinohara M, Ogonuki N, Iwano T, Lee J, Kazuki Y, Inoue K, Miki H, Takehashi M, Toyokuni S, Shinkai Y, Oshimura M, Ishino F, Ogura A, ShinoharaT. Genetic and epigenetic properties of mouse male germline stem cells during long-term culture. Development, 132: 4155-4163, 2005.
  216. Mochida K, Ohkawa M, Inoue K, ValdezJr D.M, Kasai M, and Ogura A. Birth of mice after in vitro fertilization using C57BL/6 sperm transported within epididymides at refrigerated temperatures. Theriogenology, 64: 135-143, 2005.
  217. Mochida K, Wakayama T, Takano K, Noguchi Y, Yamamoto Y, Suzuki O, MatsudaJ, and Ogura A. Birth of offspring after transfer of Mongolian gerbil (Meriones unguiculatus) embryos cryopreserved by vitrification. Mol. Reprod. Dev., 70: 464-470, 2005.
  218. Miki H, Inoue K., Kohda T, Honda A., Ogonuki N, Yuzuriha M, Mise N, Matsui Y, Baba T, Abe K, Ishino F, and Ogura A. Birth of Mice Produced by GermCell Nuclear Transfer. Genesis, 41: 81-86, 2005.
  219. Uchio-Yamada K, Manabe N, Goto Y, Anann S, Yamamoto Y, Takano K, Ogura A, Matsuda J. Decreased Expression of Matrix Metalloproteinases and TissueInhibitors of Metalloproteinase in the Kidneys of Hereditary Nephrotic (ICGN) Mice. J. Vet. Med. Sci., 67: 35-41, 2005
  220. Chuma S, Kanatsu-Shinohara M, Inoue K, Ogonuki N, Miki H, Toyokuni S, Hosokawa M, Nakatsuji N, Ogura A, and Shinohara T. Spermatogenesis from epiblast and primordial germ cells following transplantation into postnatal mouse testis. Development, 132: 117-122, 2005
  221. Kwon J, Mochida K, Wang Y.L, Sekiguchi S, Sankai T, Aoki S, Ogura A, Yoshikawa Y, Wada K. Ubiquitin C-terminal hydrolase L-1 is essential for the earlyapoptotic wave of germinal cells and for sperm quality control during Spermatogenesis. Biol. Reprod., 73: 29-35, 2005
  222. Ogonuki N, Inoue K, Miki H, Mochida K, Hatori M, Okada H, Takeiri S, Shimozawa N, Nagashima H, Sanakai T, Ogura A. Differential development of rabbit embryos following microinsemination with  sperm and spermatids. Mol. Reprod. Dev., 72: 411-417, 2005
  223. Goto Y, Uchio Yamada K, Anan S, Yamamoto Y, Ogura A, and Manabe N. Transforming growth factor-beta1 mediated up-regulation of lysyl oxidase in the kidneys of hereditary nephrotic mouse with chronic renal fibrosis. Virchows. Arch., 447: 859-868, 2005
  224. Ogura A, Inoue K, Ogonuki N, and Miki H. The present status of somatic cell cloning. Genetically Engineered Mice, Sundberg. JP and Ichiki T (eds), CRC Press, Boca Raton, USA, 125-130, 2005
  225. Miyamoto Y, Kuramitsu-Miyamoto K, Iwanaga E, Uchio-Yamada K, Yamaguchi-Yamada M, Ogura A, Manabe N. Effect of human erythropoietin (hEPO) treatment on anemia in ICR-derived glomerulonephritis (ICGN) mice. Exp. Anim., 54: 181-184, 2005
  226. Yamagata K, Yamazaki T, Yamashita M, Hara Y, Ogonuki N, Ogura A. Noninvasive visualization of molecular events in the mammalian zygote. Genesis, 43:71-79, 2005
  227. Kai M, Irie M, Okutsu T, Inoue K, Ogonuki N, Miki H, Yokoyama M, Migishima R, Muguruma K, Fujimura H, Kohda T, Ogura A, Kaneko-Ishino T, and Ishino F. The Novel Dominant Mutation Dspd Leads to a Severe Spermiogenesis Defect in Mice. Biol. Reprod., 70: 1213-1221, 2004
  228. Yamaguchi-Yamada M, Manabe N, Goto Y, Anan S, Miyamoto K, Miyamoto Y, Nagao M, Yamamoto Y, and Ogura A. Improvement of anemia associated with chronic renal failure by recombinant human erythropoietin treatment in ICR-derived glomerulonephritis (ICGN) mice. J. Vet. Med. Sci., 66: 883-886, 2004
  229. Yamaguchi-Yamada M, Manabe N, Uchio-Yamada K, Akashi N, Goto Y, Miyamoto Y, Nagao M, Yamamoto Y, Ogura A, and Miyamoto H. Anemia with chronic renal disorder and disrupted metabolism of erythropoietin in ICR-derived glomerulonephritis (ICGN) mice. J. Vet. Med. Sci., 66: 423-431, 2004
  230. Nakamura T, Yao R, Ogawa T, Suzuki T, Ito C, Tsunekawa N, Inoue K, Ajima R, Miyasaka T, Yoshida Y, Ogura A, Toshimori K, Noce T, Yamamoto T, and Noda T. Oligo-astheno-teratozoospermia in mice lacking CCR4-associated factor 1, a novel regulator of RXRb. Nat. Genet., 36: 528-533, 2004
  231. Ohgane J, Wakayama T, Senda S, Yamazaki Y, Inoue K, Ogura A, Marh J, Tanaka S, Yanagimachi R, and Shiota K. The Sall3 locus is an epigenetic hotspot of aberrant DNA methylation associated with placentomegaly of cloned mice. Genes Cells, 9: 253-60, 2004
  232. Kanatsu-Shinohara M, Inoue K, Lee J, Yoshimoto M, Ogonuki N, Miki H, Baba S, Kato T, Kazuki Y, Toyokuni S, Oshimura M, Heike T, Nakahata T, Ishino F, Ogura A, and Shinohara T. Generation of pluripotent stem cells from neonatal mouse testis. Cell, 119: 1001-1012, 2004
  233. Miki H, Inoue K, Ogonuki N, Mochida K, Nagashima H, Baba T, and Ogura A. Cytoplasmic Asters are Required for Progression past the First Cell Cycle in Cloned Mouse Embryos. Biol. Reprod., 71: 2022-2028, 2004
  234. Miki H, Lee J, Inoue K, Ogonuki N, Noguchi Y, Mochida K, Kohda T, Nagashima H, Ishino F, and Ogura A. Microinsemination with first-wave round spermatids from immature male mice. J. Reprod. Dev., 50: 131-137, 2004
  235. Uchio K, Manabe N, Yamatuchi-Yamada M, Goto Y, Yamamoto Y, Ogura A, and Miyamoto H. Changes in the localization of type I, III and IV collagen mRNAs in the kidneys of hereditary nephrotic (ICGN) mice with renal fibrosis. J. Vet. Med. Sci., 66: 123-128, 2004
  236. Fulka Jr J, Miyashita N, Nagai T, and Ogura A. Do cloned mammals skip a reprogramming step? Nat. Biotechnol., 22: 25-26, 2004
  237. Goto Y, Manabe N, Uchio K, Yamaguchi-Yamada M, Inoue N, Yamamoto Y, Ogura A, Nagano N, and Miyamoto H. Augmented cytoplasmic Smad4 induces acceleration of TGF-beta1 signaling in renal tubulointerstitial cells of hereditary nephrotic ICGN mice with chronic renal fibrosis; possible role for myofibroblastic differentiation. Cell Tissue Res., 315: 209-221, 2004
  238. Manonmani P, Okada H, Ogonuki N, Uda A, Ogura A, Yoshida T, and Sankai T. Fertilization and preimplantation development of mouse oocytes after prolonged incubation with caffeine.Reprod. Med. Biol., 3: 245-251, 2004.
  239. Inoue K, Ogonuki N, Yamamoto Y, Takano K, Miki H, Mochida K, and Ogura A. Tissue-specific distribution of donor mitochondrial DNA in cloned mice produced by somatic cell nuclear transfer.Genesis , 39: 79-83, 2004.
  240. Masujin K, Okada T, Tsuji T, Ishii Y, Takano K, Matsuda J, Ogura A, and Kunieda T. A mutation in the serum and glucocorticoid-inducible kinase-like kinase (Sgkl) gene is responsible for defective hair growth in mice. DNA Research, 11: 371-379, 2004
  241. Kanatsu-Shinohara M, Ogonuki N, Inoue K, Miki H, Ogura A, Toyokuni S, and Shinohara T. Long-Term Proliferation in Culture and Germline Transmission of Mouse Male Germline Stem Cells. Biol. Reprod., 69: 612-616, 2003
  242. Kanatsu-Shinohara M, Ogonuki N, Inoue K, Ogura A, Toyokuni K, Kogishi T, Honjo T, Shinohara T. Allogeneic offspring produced by male germ line stem cell transplantation into infertile mouse testis. Biol. Reprod., 68: 167-173, 2003
  243. Kanatsu-Shinohara M, Ogonuki N, Inoue K, Ogura A, Toyokuni S, and Shinohara T. Restoration of fertility in infertile mice by transplantation of cryopreserved male germline stem cells. Hum. Reprod., 18: 2660-2667, 2003
  244. Ogonuki N, Mochida K, Inoue K, Matsuda J, Yamamoto Y, Takano K, Ogura A. Fertilization of Oocytes and Birth of Normal Pups Following intracytoplasmic Injection with Spermatids in Mastomys (Praomys coucha). Biol. Reprod., 68: 1821-1827, 2003
  245. Ogonuki N, Tsuchiya H, Hirose Y, Okada H, Ogura A, Sankai T. Pregnancy by the tubal transfer of embryos developed after injection of round spermatids into oocyte cytoplasm of the cynomolgus monkey (Macaca fascicularis). Hum. Reprod., 18: 1273-1280, 2003
  246. Ogura A, Ogonuki N, Inoue K, Mochida K. New microinsemination techniques for laboratory animals. Theriogenology, 59: 87-94, 2003
  247. Inoue K, Ogonuki N, Mochida K, Yamamoto Y, Takano K, Kohda T, Ishino F, and Ogura A. Effects of Donor Cell Type and Genotype on the Efficiency of Mouse Somatic Cell Cloning. Biol. Reprod., 69: 1394-1400, 2003
  248. Lee J, Inoue K, Ono R, Ogonuki N, Kohda K, Kaneko Ishino T, Ogura A, Ishino F. Erasing genomic imprinting memory in mouse clone embryos produced from day 11.5 primordial germ cells. Development, 129: 1807-1817, 2002
  249. Kim JM, Ogura A, Nagata M, Aoki F. Analysis of the mechanism for chromatin remodeling in the embryos reconstructed by somatic nuclear transfer. Biol. Reprod., 67: 760-766, 2002
  250. Kanatsu-Shinohara M, Ogura A, Ikegawa M, Inoue K, Ogonuki N, Tashiro K, Toyokuni S, Honjo T, Shinohara T. Adenovirus-mediated gene delivery and in vitro microinsemination produce offspring from infertile male mice. Proc. Natl. Acad. Sci. USA, 99: 1383-1388, 2002
  251. Kobayashi S, Kohda T, Ichikawa H, Ogura A, Ohki M, Kaneko-Ishino T, Ishino F. Paternal Expression of a Novel Imprinted Gene, Peg12/Frat3, in the mouse 7C Region Homologous to the Prader-Willi Syndrome Region. Biochem. Biophys. Res. Commun., 290: 403-408, 2002
  252. Kohda T, Lee J, Inoue K, Ogonuki N, Wakisaka-Saito N, Kaneko-Ishino T, Ogura A, and Ishino F. Epigenetic regulation in mammalian development and dysfunction; the effects of somatic cloning and genomic imprinting. International Congress Series, 1246: 151-159, 2002
  253. Kashiwabara S, Noguchi J, Zhuang T, Ohmura K, Honda A, Sugiura S, Miyamoto K, Takahashi S, Inoue K, Ogura A, Baba T. Regulation of spermatogenesis by testis-specific, cytoplasmic poly(A) polymerase TPAP. Science, 298: 1999-2002, 2002
  254. Shinohara T, Inoue K, Ogonuki N, Kanatsu-Shinohara M, Miki H, Nakata K, Kurome M, Nagashima H, Toyokuni S, Kogishi K, Honjo T, Ogura A. Birth of offspring following transplantation of cryopreserved immature testicular piece and in vitro microinsemination. Hum. Reprod., 17: 3039-3045, 2002
  255. Ogonuki N, Inoue K, Yamamoto Y, Noguchi Y, Tanemura K, Suzuki O, Nakayama H, Doi K, Ohtomo K, Satoh M, Nshida A, Ogura A. Early death of mice cloned from somatic cells. Nat. Genet., 30: 253-254, 2002
  256. Ogura A, Inoue K, Ogonuki N, Lee J, Kohda T, Ishino F. Phenotypic effects of somatic cell cloning in the mouse. Cloning Stem Cell, 4: 397-405, 2002
  257. Ogura A, Ogonuki N, Inoue K. Microinsemination and nuclear transfer with male germ cells. In: Principles of Cloning, edited by Cibelli, J. B., Lanza, R., Campbell, K., and West, M. D. San Diego:Academic Pres, pp.175-186, 2002
  258. Inoue,K., Kohda, T., Lee, J., Ogonuki, N., Mochida, K., Noguchi, Y., Tanemura, K., Kaneko Ishhino, T., Ishino, F. and Ogura, A. Faithful expression of imprinted genes in cloned mice. Science, 295: 297, 2002
  259. Inoue K, Ogonuki N, Yamamoto Y, Noguchi Y, Takeiri S, Nakata K, Miki H, Kurome M, Nagashima H, Ogura A. Improved postimplantation development of rabbit nuclear transfer embryos by activation with inositol 1,4,5-trisphosphate. Cloning Stem Cell, 4: 311-317, 2002
  260. Inoue K, Ogura A, Hayashi J. Production of mitochondrial DNA transgenic mice using zygotes. Methods, 26: 358-63, 2002
  261. Suzuki O, Mochida K, Yamamoto Y, Noguchi Y, Takano K, Matsuda J, Ogura A. Comparison of glycoprotein hormone alpha-subunits of laboratory animals. Mol. Reprod. Dev., 62: 335-342, 2002
  262. Ikawa M, Tergaonkar V, Ogura A, Ogonuki N, Inoue K, Verma, IM. Restoration of spermatogenesis by lentiviral gene transfer: Offspring from infertile mice. Proc. Natl. Acad. Sci. USA, 99: 7524-7529, 2002
  263. Ohba Y, Ikuta K, Ogura A, Matsuda J, Mochizuki N, Nagashima K, Kurokawa K, Mayer BJ, Maki K, Miyazaki J, Matsuda M. Requirement of C3G-dependent Rap1 activation for cell adhesion and embryogenesis. EMBO. J., 20: 3333-3341, 2001
  264. Nakada K, Inoue K, Chen CS, Nonaka I, Goto Y, Ogura A, Hayashi JI. Correlation of functional and ultrastructural abnormalities of mitochondria in mouse heart carrying a pathogenic mutant mtDNA with a 4696-bp deletion. Biochem. Biophys. Res. Commun., 288: 901-907, 2001
  265. Nakada K, Inoue K, Ono T, Isobe K, Ogura A, Goto Y, Nonaka I, Hayashi JI.  Inter-mitochondrial complementation: Mitochondria-specific system preventing mice from expression of disease phenotypes by mutant mtDNA. Nat. Med., 7: 934-939, 2001
  266. Yamaguchi M, Manabe N, Uchio-Yamada K, Akashi N, Yamamoto Y, Ogura A, Miyamoto H. Localization of proliferative and apoptotic cells in the kidneys of ICR-derived glomerulonephritis (ICGN) mice. J. Vet. Med. Sci., 63: 781-787, 2001
  267. Itoh M, Matsuda J, Suzuki O, Ogura A, Oshima A, Tai T, Suzuki Y, Takashima S. Development of lysosomal storage in mice with targeted disruption of the beta-galactosidase gene: a model of human GM1-gangliosidosis. Brain Dev., 23: 379-384, 2001
  268. Ogonuki N, Sankai T, Yagami K, Shikano T, Oda S, Miyazaki S, Ogura A. Activity of a sperm-borne oocyte-activating factor in spermatozoa and spermatogenic cells from cynomolgus monkeys and its localization after oocyte activation. Biol. Reprod., 65: 351-357, 2001
  269. Ogura A, Inoue K, Mochida K, Ogonuki N, Yanagimachi R. Fertilization without spermatozoa. Ital. J. Anat. Embryol., 106: 3-10, 2001
  270. Ogura A, Ogonuki N, Takano K, Inoue K. Microinsemination, nuclear transfer, and cytoplasmic transfer: the application of new reproductive engineering techniques to mouse genetics. Mamm. Genome, 12: 803-812, 2001
  271. Shi F, Mochida K, Ogura A, Matsuda J, Suzuki O, Watanabe G, Hutz RJ, Tsonis CG, Suzuki AK, Taya K. Follicle selection in cyclic guinea pigs with active immunization against inhibin a-subunit. Life Sci., 66: 2489-2497, 2000
  272. Shi F, Mochida K, Ogura A, Matsuda J, Suzuki O, Watanabe G, Hutz RJ, Tsonis CG, Suzuki AK, Taya K. Development of embryos in superovulated guinea pigs following active immunization against inhibin alpha-subunit. Endocr. J., 47: 451-459, 2000
  273. Shi FX, Mochida K, Suzuki O, Matsuda J, Ogura A, Ozawa M, Watanabe G, Suzuki AK, Taya K. Ovarian localization of immunoglobulin G and inhibin alpha-subunit in guinea pigs after passive immunization against the inhibin alpha-subunit. J. Reprod. Dev., 46: 293-299, 2000
  274. Miyado K, Yamada G, Yamada S, Hasuwa H, Nakamura Y, Ryu F, Suzuki K, Kosai K, Inoue K, Ogura A, Okabe M, Mekada E. Requirement of CD9 on the egg plasma membrane for fertilization. Science, 287: 321-324, 2000
  275. Nagaoka H, Takahashi Y, Hayashi R, Nakamura T, Ishii K, Matsuda J, Ogura A, Shirakata Y, Karasuyama H, Sudo T, Nishikawa S, Tsubata T, Mizuochi T, Asano T, Sakano H, Takemori T. Ras mediates effector pathways responsible for pre-B cell survival, which is essential for the developmental progression to the late pre-B cell stage. J. Exp. Med., 192: 171-181, 200
  276. Wakayama T, Shinkai Y, Tamashiro KLK, Blanchard RJ, Caroline K, Ogura A, Tanemura K, Mombaerts P, Perry ACF, Yanagimachi R. Sequential cloning of mice to six generations. Nature, 407: 318-319, 2000
  277. Kobayashi S, Wagatsuma H, Ono R, Ichikawa H, Yamazaki M, TAshiro H, Aisaka K, Miyoshi N, Kohda T, Ogura A, Ohki M, Kaneko-Ishino T, Ishino F. Mouse Peg9/Dlk1 and human PEG9/DLK1 are paternally expressed imprinted genes closely located to the maternally expressed genes: mouse Meg3/Gtl2 and human MEG3. Genes Cells, 5: 1029-1037, 2000
  278. Mochida K, Yamamoto Y, Noguchi Y, Takano K, Matsuda J, Ogura A. Survival and subsequent development in vitro of hamster embryos after exposure to cryoprotectant solutions. J. Assist. Reprod. Genet., 17: 182-185, 2000
  279. Uchio K, Manabe N, Tamura K, Miyamoto M, Yamaguchi M, Ogura A, Yamamoto Y, Miyamoto H. Decreased matrix metalloproteinase activity in the kidneys of hereditary nephrotic mice (ICGN strain). Nephron., 86: 145-151, 2000
  280. Ogura A, Inoue K, Ogonuki N, Noguchi A, Takano K, Nagano R, Suzuki O, Lee J, Ishino F, Matsuda J. Production of male clone mice from fresh, cultured, and cryopreserved immature Sertoli cells. Biol. Reprod., 62: 1579-1584, 2000
  281. Ogura A, Inoue K, Ogonuki N, Suzuki O, Mochida K, Matsuda J, Sankai T. Recent advances in the microinsemination of laboratory animals. Int. J. Androl., 23: 60-62, 2000
  282. Ogura A, Inoue K, Takano K, Wakayama T, Yanagimachi R. Birth of mice after nuclear transfer by electrofusion using tail tip cells.Mol. Reprod. Dev., 57: 55-59, 2000
  283. Shitara H, Kaneda H, Sato A, Inoue K, Ogura A, Yonekawa H. Hayashi JI Selective and continuous elimination of mitochondria microinjected into mouse eggs from spermatids, but not from liver cells, occurs throughout embryogenesis. Genetics, 156: 1277-84, 2000
  284. Inoue K, Nakada K, Ogura A, Isobe K, Goto Y, Nonaka I, Hayashi J. Generation of mice with mitochondrial dysfunction by introducing mouse mtDNA carrying a deletion into zygotes. Nat. Genet., 26: 176-181, 2000