Goal:
Our life begins with fertilization and progresses through changes such as implantation, birth, growth, and aging, and this cycle is passed on to the next generation through the germ cells.
This sequence of processes is called the “life cycle”.
In our laboratory, we aim to elucidate various life phenomena in the life cycle by using developmental engineering technology with oocytes, sperm, and embryos, as well as genetic and epigenetic analysis technology. Furthermore, based on the knowledge obtained from these studies, we will contribute to establishing more advanced developmental engineering technologies to maintain and supply high-quality and reliable bioresources.
Activities:
1. Development of Advanced Reproductive Engineering Technologies
We aim to develop more efficient and versatile reproductive techniques based on cryopreservation of embryos and gametes, intracytoplasmic sperm injection (ICSI), and somatic cell nuclear transfer (SCNT).
2. Elucidation of the Life Cycle Using Next-Generation Technologies
Using cutting-edge tools such as next-generation sequencing and live imaging, we seek to uncover various biological phenomena that occur throughout the life cycle, including fertilization, implantation, development, aging, and inheritance to the next generation.
3. Development of Model Systems for Understanding Life Cycle
We aim to construct model systems that facilitate an understanding of biological phenomena throughout the life cycle by developing stem cells and model animals, as well as implementing AI-driven and automated analytical systems.